A Continuous Bovine Kidney Cell Line Constitutively Expressing Bovine V 6 Integrin Has Increased Susceptibility to Foot-and-Mouth Disease Virus
نویسندگان
چکیده
Foreign Animal Disease Research Unit, United States Department of Agriculture, Agricultural Research Service, Plum Island Animal Disease Center, Greenport, New York, USA; The McConnell Group, Inc., Rockville, Maryland, USA; Foreign Animal Disease Diagnostic Laboratory, United States Department of Agriculture, Animal and Plant Health Inspection Service, Plum Island Animal Disease Center, Greenport, New York, USA
منابع مشابه
Correction for LaRocco et al., A Continuous Bovine Kidney Cell Line Constitutively Expressing Bovine αVβ6 Integrin Has Increased Susceptibility to Foot-and-Mouth Disease Virus.
Foot-and-mouth disease (FMD) is a worldwide problem limiting the trade of animals and their products from affected countries. The rapid isolation, serotyping, and vaccine matching of FMD virus from disease outbreaks is critical for enabling the implementation of effective vaccination programs and to stop the spread of infection during outbreaks. Some primary cells have been shown to be highly s...
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In this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in Iran. The cells were originating from two-day-old normal male calf of Holstein breed. The cell cultures were continuously passaged following complete proliferation of primary cells. The specific properties or characteristics of the cell were defined using cytogenet...
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Abstract Background and Aims: To identify and isolation of viruses a susceptible cell is need which can be primary or line. The use of primary cells is laborious, time consuming and expensive, while the use of cell lines is much easier and faster. IRKHBK cell line was originated from primary cells of bovine kidney by continuous passage. The aim of this study was to introduce the IRKHBK cell ...
متن کاملFoot-and-mouth disease virus receptors: comparison of bovine alpha(V) integrin utilization by type A and O viruses.
Three members of the alpha(V) integrin family of cellular receptors, alpha(V)beta(1), alpha(V)beta(3), and alpha(V)beta(6), have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro. The virus interacts with these receptors via a highly conserved arginine-glycine-aspartic acid (RGD) amino acid sequence motif located within the betaG-betaH (G-H) loop of VP1. Other alpha(...
متن کاملFoot-and-Mouth Disease Virus Receptors: Comparison of Bovine V Integrin Utilization by Type A and O Viruses
Three members of the V integrin family of cellular receptors, V 1, V 3, and V 6, have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro. The virus interacts with these receptors via a highly conserved arginine-glycine-aspartic acid (RGD) amino acid sequence motif located within the GH (G-H) loop of VP1. Other V integrins, as well as several other integrins, recognize...
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